Through games of Jan. 2, 2022:
| # | School (No. 1 votes) | W-L | Pts. | Prev. |
| 1 | Randolph-Macon (15) | 10-1 | 611 | 2 |
| 2 | UW-Platteville (9) | 13-0 | 602 | 3 |
| 3 | Illinois Wesleyan (1) | 9-2 | 570 | 4 |
| 4 | UW-Oshkosh | 12-1 | 540 | 5 |
| 5 | Yeshiva | 14-1 | 477 | 1 |
| 6 | St. Joseph (Conn.) | 8-0 | 448 | 7 |
| 7 | Washington U. | 10-1 | 437 | 15 |
| 8 | Marietta | 8-2 | 434 | 8 |
| 9 | Wheaton (Ill.) | 11-2 | 395 | 6 |
| 10 | Christopher Newport | 13-2 | 386 | 12 |
| 11 | UW-La Crosse | 9-2 | 384 | 9 |
| 12 | Johns Hopkins | 7-1 | 359 | 11 |
| 13 | Whitworth | 9-1 | 322 | 13 |
| 14 | Elmhurst | 11-2 | 289 | 14 |
| 15 | Mount Union | 9-1 | 257 | 16 |
| 16 | Roanoke | 9-2 | 253 | 10 |
| 17 | Williams | 9-0 | 218 | 17 |
| 18 | Swarthmore | 9-1 | 191 | 18 |
| 19 | Mary Hardin-Baylor | 9-1 | 172 | 19 |
| 20 | Maryville (Tenn.) | 11-1 | 167 | 23 |
| 21 | Heidelberg | 9-1 | 155 | 22 |
| 22 | Hardin-Simmons | 10-1 | 104 | 25 |
| 23 | Wesleyan | 11-1 | 89 | -- |
| 24 | WPI | 8-1 | 51 | -- |
| 25 | RPI | 9-1 | 39 | 21 |
Dropped out: No. 20 Amherst; No. 24 DeSales.
Others receiving votes: Oswego 25; Case Western Reserve 24; Amherst 22; DeSales 15; Berry 14; Trinity (Texas) 14; Emory 11; Tufts 9; Wartburg 9; Brandeis 8; Augsburg 6; Rochester 5; Stockton 5; Chapman 3; Hampden-Sydney 2; Nazareth 2; LeTourneau 1.
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly. Points are awarded on a 25-24-23-22-etc. basis.